The Complementary Structure of Deoxyribonucleic Acid

F. H. C. Crick, J. D. Watson

Abstract

This paper describes a possible structure for the paracrystalline form of the sodium salt of deoxyribonucleic acid. The structure consists of two DNA chains wound helically round a common axis, and held together by hydrogen bonds between specific pairs of bases. The assumptions made in deriving the structure are described, and co-ordinates are given for the principal atoms. The structure of the crystalline form is discussed briefly.